Ocular abnormalities in thin basement membrane disease
نویسندگان
چکیده
منابع مشابه
Ocular abnormalities in thin basement membrane disease.
AIM/BACKGROUND Alport syndrome is an X linked disease that results in renal failure, deafness, and ocular abnormalities including a dot and fleck retinopathy and anterior lenticonus. The ultrastructural appearance of the glomerular basement membrane in thin basement membrane disease (TBMD) resembles that seen in some patients with Alport syndrome, and in some cases this disease is inherited too...
متن کاملDisease of the Month Thin Basement Membrane Nephropathy
T hin basement membrane nephropathy (TBMN) is the most common cause of persistent hematuria in children and adults, the other main causes being IgA nephropathy and Alport syndrome (1–3). In addition to hematuria, patients with TBMN usually have minimal proteinuria, normal renal function, and uniformly thinned glomerular basement membranes (GBM), as determined by electron microscopy. TBMN, which...
متن کاملClinical and morphological aspects of thin glomerular basement membrane disease.
The report presents the results of investigations carried out in 63 patients (49 children and 14 adults) with thin glomerular basement membrane disease. Of 49 children, 13 came from nine families with family members suffering from kidney diseases (mostly manifested by haematuria). In the group of children, the most frequent initial clinical symptom (noted in 29 cases) was isolated haematuria, m...
متن کاملThin basement membrane syndrome in adults.
Eight (two men, six women) cases of adult thin basement membrane syndrome were studied to clarify the clinicopathological characteristics of the disease. The average age at the time of biopsy was 40 years. All the patients had persistent microscopic haematuria, normal renal function, and normal blood pressure, with the exception of one who was hypotensive. Most of them had persistent or transie...
متن کاملThin basement membrane nephropathy and renal transplantation.
The clinical implications of thin basement membrane nephropathy (TBMN) in renal transplantation must be considered from the perspectives of both the allograft recipient and the donor. Most individuals with TBMN have a benign course, but some develop end-stage renal failure (ESRF) and undergo transplantation. ESRF in patients with TBMN often results from the presence of additional glomerular or ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1997
ISSN: 0007-1161
DOI: 10.1136/bjo.81.5.373